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Previous research shows that taste receptors for bitter compounds (T2Rs) are present in tissues outside the mouth, including the brain, heart, reproductive system, and respiratory system, suggesting a role beyond taste perception

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The epithelial tissue disorganization and crypt disorganization were divided into five categories according to the degree of disorganization of each tissue

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PMID: 41155596 Int Immunopharmacol CGRP alleviates epilepsy via JAK1-STAT1-P2RX7 signaling: a novel neuroprotective axis targeting neuronal damage