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While researchers note that the LD50 (lethal dose) for GHK-Cu in murine models equates to an impossibly massive single dose of roughly 23,000mg for a 70kg human adultrendering acute lethal toxicity highly improbable at the standard aesthetic therapeutic doses of 5-50mgthe long-term cumulative effects of daily copper peptide injections remain entirely unmapped in human populations

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10.18632/oncotarget.11168 Oncotarget 32 PeiH.JiangT.LiuG.LiZ.LuoK.AnJ.et al (2016)

Its ability to promote collagen synthesis and new blood vessel formation at the injury site makes it particularly relevant for the knee's complex connective tissue structures

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