In naturally aged mouse models (1820 months old), daily oral administration of 5-amino-1mq capsules for 12 consecutive weeks significantly reduced NNMT activity and increased NAD+ levels in various tissues (liver, kidney, adipose tissue), along with markedly elevated expression of SIRT1 and SIRT3 proteins
As for the pill - I have not had a good experience myself - it just did not do good things for my body, however I have heard in younger women it does marvels for regulating periods - so am surprised you are getting intermittent bleeding - worth another poke at the docs perhaps
If you have symptoms of deficiency or risk factors such as metformin use, speak with your GP about appropriate testing and treatment
You have been so awesome and I always appreciate your advice
Most at home B12 injection protocols use a standard dose of 1000 mcg (1 mg) per injection
High levels of B12 are a warning sign: While low serum cobalamin levels do not necessarily imply deficiency, an abnormally high serum cobalamin level forms a warning sign requiring exclusion of a number of serious underlying pathologies