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NAC also improved insulin resistance, suppressed fat from accumulating in the liver, and stimulated thermogenic (fat-burning) genes in the mice, suggesting that NAC may help protect against obesity and obesity-associated metabolic disorders

I started with one ankle and could feel the difference between the two feet

doi: 10.1007/s00395-021-00873-9 Darsalia V, Hua S, Larsson M, et al

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Clinically, prioritize agents supported by evidence from outcome trials in patients with established ASCVD or CKD , even if metformin would traditionally precede incretin therapy

And thats the case here, is that the antibodies, the natural immunity antibodies are important, but theyre not really realistic if you want to reduce the burden of illness and possible mortality