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Experiments indicate that PKA is the predominant and most physiologically relevant effector through which beta agonists cause bronchial smooth muscle relaxation (Morgan et al, 2014)
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Hence, current efforts are directed towards the development of novel agents, implementation of predictive biomarkers and design of combination strategies to improve patient outcomes
51, Jan
Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, et al
