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For its first Super Bowl ad appearance, the company is launching "Healthier on Ro," a campaign featuring tennis legend Serena Williams that aims to rebrand weight-loss medication from a cosmetic shortcut to a serious clinical intervention that drives the health benefits commonly associated with weight loss
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However, severity and tolerance vary widely from person to person
What that wisdom missed - and what a small group of academic endocrinologists, most prominently Richard DiMarchi's group at Indiana University, had begun to argue aggressively through the early 2010s - was that glucagon's metabolic role is not just "raise glucose." It is a broader lever on hepatic lipid handling, mitochondrial uncoupling, brown-fat activation, and energy expenditure
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