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No evidence supports its use over or in addition to evidence-based orthobiologic interventions

Mean differences between GLP-1 based therapy and control patients in the changes from baseline were 5.47 [9.55, 1.39] mg/dl (P = 0.009

the larger the number, the greater the improvement

Scale Weight vs

(3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexanoylamino)-9-benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide

[13] The relevance to the blend is indirect but real: whatever glucose-metabolic footprint the GH axis carries when stimulated by an oral secretagogue is a reasonable prior for what a GHRH+GHRP stimulus might do, and long-term data that would actually characterize such risks for this blend simply do not exist