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These Inflammatory factors activate astrocytes to over express BACE1 enzyme and produce excessive amounts of A proteins (Blasko et al., 2000)

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SA synthesis is regulated by UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) that catalyzes rate limiting steps

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A subfamily of CYPs thought to be involved with plant secondary metabolism is CYP72A, as these genes are expressed in response to various plant stress conditions