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ROS exert cytotoxic effects, mainly by promoting rapid peroxidation of membrane lipids (186)

Some individuals have genetic variations in glutathione synthesis genes (GCLC, GCLM, GSS) or detoxification enzymes (GST family) that may influence baseline capacity

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The second, TB-500, is a synthetic acetylated heptapeptide, Ac-LKKTETQ, corresponding to amino acids 17 to 23 of thymosin beta-4