Bimagrumab (Novartis/Versanis): Mechanistically distinct, this is an antibody that blocks a pathway limiting muscle growth
The mechanisms underlying these hepatoprotective effects include reduced hepatic lipogenesis (fat production), enhanced fatty acid oxidation, and decreased inflammatory cytokine production
MedTech stocks continue to feel pressure from glucagon-like peptide-1 (GLP-1) drugs for obesity, based primarily on speculation, and despite strong third-quarter performances from many firms in this sector
Thats a problem, both in research and in practice. The drugs work best not as a replacement for healthy habits, he said, but as a tool that makes those habits far more achievable
In a cohort of 30 euthyroid human study participants, a negative correlation between free T3 levels and total cholesterol levels was observed (Supplementary Fig
A cohort study found that GLP-1RAs were associated with a reduced risk of hepatic decompensation and mortality in individuals with type 2 diabetes cirrhosis (Yen et al., 2024)