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Reported risks include increased heart rate, jitteriness, anxiety, and sleep disturbances, particularly for people who are sensitive to caffeine or similar stimulants

Dynamic contrast-enhanced magnetic resonance imaging A commonly employed imaging technique to measure subtle BBB permeability is DCE MRI, which utilizes continuous scanning prior to and after injection of an intravenously administered gadolinium-based contrast agent (GBCA) to measure the change in gadolinium concentration in the brain (Heye et al., 2014

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Although stress tends to be more of a mental or emotional issue, it can have physical manifestations