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Prolonged deficiency leads to numbness, tingling, and nerve damage that's hard to reverse

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1 Numerous medications have been associated with CI, including constipation-inducing drugs (eg, opioids, muscarinic antagonists), diuretics (eg, furosemide), nonsteroidal anti-inflammatory drugs, illicit drugs (eg, cocaine), digoxin, hormonal therapies (eg, combined oral contraceptives), and laxatives

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