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Spremovic Radenovic S, Pupovac M, Andjic M, et al

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Same drug, 325 a week to 7,400 a month

The recommended dilution factor for different samples is as follows (for reference only): Note: The diluent is normal saline (0.9% NaCl) or PBS (0.01 M, pH 7.4).

A key challenge stems from the structural complexity of conjugating a large antibody (~150 kDa) with a multifunctional PROTAC, often generating heterogeneous species that are difficult to optimize

The key factor is how fast a person loses weight, not the specific drug