As mechanistic insights into iron homeostasis, lipid peroxidation, and immunometabolic interactions continue to deepen, alongside progress in drug delivery, gene editing, and regenerative medicine, therapies targeting ferroptosis may represent a promising new paradigm in OA management, ultimately enhancing joint function and overall quality of life for affected individuals
Tryptophan deficiency aggravates disease severity (90), and indole also has a role in the maintenance of gut health (91)
Most patients begin to notice appetite changes within the first few weeks
Next-generation beneficial microbes: the case of Akkermansia muciniphila
Does the Wegovy pill cause less nausea than the injection
Ongoing treatment: If well-tolerated, increase to 0.5 mg once weekly starting from week 5