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Macrophage migration inhibitory factor promotes breast cancer metastasis via activation of HMGB1/TLR4/NF kappa B axis

Rimmele U, Spillmann M, Brtschi C, Wolf OT, Weber CS, Ehlert U, et al

It is also vital for immune function, as it enhances the bodys defence against infections

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Interestingly, maternal IF has been shown to significantly decrease levels of DNA methyltransferase in offspring, suggesting a potential intergenerational impact on DNA methylation dynamics [89]