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This is namely because "there is insufficient evidence on whether it would cause harm to humans" New England Baptist Hospital #sportsmedicine .

The digest was filtered through a 70-m mesh and centrifuged using a 28.7% Nycodenz gradient (Nycomed PharmaAS, Oslo, Norway)

If still not dissolving, the peptide may have degraded before reconstitution

Mol Cell Biol 15 : 35163522 Werner H, Stannard B, Bach MA, Roberts Jr CT, LeRoith D (1991) Regulation of insulin-like growth factor I receptor gene expression in normal and pathological states

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doi: 10.1096/fj.201900386RR 105 JacksonDNTheissAL