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CJC-1295 without DAC occupies the sweet spot: longer-acting than sermorelin (which degrades too fast for reliable clinical effect), shorter-acting than DAC (which sacrifices pulsatility), and considerably cheaper than tesamorelin (the only FDA-approved option in this class)

1 (2020): 889, 10.1038/s41467-020-14734-x

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Interestingly ACSL4 was preferentially expressed in a panel of basal-like breast cancer cell lines and predicted their sensitivity to ferroptosis ( Figure 2 Conclusion and Remaining Questions During past decade, investigation of ferroptosis from both aspects: induction and prevention, has become a topic of interests for numerous different pathologies

Recognition of this phenotype may enable development of dual-pathway targeted therapies (Zhao et al., 2021