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In this case, despite markedly low vitamin B12 levels and deep sensory impairment, there were no findings of anemia, upper motor neuron signs (such as hyperreflexia or a positive Babinski sign), or abnormal signal intensities in the posterior columns of the cervical spinal cord on MRI [7]

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These are experimental patterns

Researchers are exploring oral and nasal delivery systems, but none are commercially available

A 2022 UK study found that of those with B12 deficiency, pernicious anaemia was the underlying diagnosis in nearly half of the cases, making it a major cause