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In general, acyl-CoA synthetase long-chain family member 4 (ACSL4), lysophosphatidylcholine acyltransferase 3 (LPCAT3), and lipoxygenases (e.g., 15-LO) promote the peroxidation of phospholipids containing PUFA during ferroptosis [104]

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Dehydrozingerone inhibits renal lipotoxicity in high-fat diet-induced obese mice

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Common interactions include NSAIDs, certain antibiotics, HIV medications, immunosuppressants, diuretics, and anticoagulants

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