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Furthermore, studies found that LPS-induced macrophages in patients can release HMGB1 via extracellular vesicles (EVs), subsequently activating the NLRP3 inflammasome to trigger hepatocyte pyroptosis [46]

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10.4161/cc.5.14.2918 Cell Cycle 193 TyndallS

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Endogenous tryptophan metabolite 5-Methoxytryptophan inhibits pulmonary fibrosis by downregulating the TGF-beta/SMAD3 and PI3K/AKT signaling pathway

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It contains Vitamin B1 (Thiamine Hydrochloride), Vitamin B6 (Pyridoxine Hydrochloride), and Vitamin B12 (Cyanocobalamin)

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doi: 10.1016/s0891-5849(99)00177-x

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