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These results suggested that keloid fibroblasts underwent pro-senescence regulation earlier compared with normal skin fibroblasts via p53-pS15 under serum limitation stimulus, and p53-pS15 and FOXO4 translocated from the nucleus to the cytoplasm during FOXO4-DRI treatment

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3.2.2 Regulatory T cells Tregs maintain immune homeostasis suppressing excessive inflammation (117)

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In addition, regulated ROS equilibrium is necessary not only for pollen development but also for pollen germination and pollen tube tip growth