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da Rocha CF, de Medeiros Souza Lima Y, Carvalho HO, Pinto RC, Ferreira IM, Castro AN, et al

Current guidelines, such as those from the European Society of Cardiology (ESC), recommend the use of SGLT-2i as a first-line treatment in patients with T2DM with multiple atherosclerotic cardiovascular disease (ASCVD) risk factors, established ASCVD, patients with T2DM and HFrEF to reduce the risk of heart failure hospitalization and cardiovascular death [13]

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This article outlines what is currently known about its dosing, mechanism, suitability, safety profile, and regulatory status

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