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Quad-agonist peptides (GLP-1/GIP/glucagon/GCG analogs): In preclinical development, these add galanin or other receptor targets to the triple-agonist backbone
Retatrutide is a triple-agonist research peptide studied for its interaction with GIP, GLP-1, and glucagon receptors
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DPP-4 inhibitors appear to have additive A1C-lowering effects in combination with other oral agents used to treat diabetes
Goggins, M
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