In LC-MS/MS, intact peptide ions are broken into smaller fragments, producing patterns (such as b-ions and y-ions) that reveal the amino acid sequence and location of modifications
Greig et al Exendin-4 Is a High Potency Agonist and Truncated exendin-(9-39)-amide an Antagonist at the Glucagon-Like Peptide 1-(7-36)-amide Receptor of Insulin-Secreting Beta-Cells JBC
The chemicals can then diffuse to nearby neurons, exciting or inhibiting activity in those recipient cells
Smooth muscle contraction and relaxation
Furthermore, the secretion index, which represents the absolute insulinotropic effect calculated by dividing the insulin level under high-glucose conditions by that under low-glucose conditions, was evaluated
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