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Melanoma: Nail matrix melanoma is the most frequently observed melanoma subtype in blacks and Asians

In the fed group, after the overnight fast, subjects consumed a high-caloric, high-fat breakfast (4058 kJ, 27 energy percent [E%] carbohydrate, 60 E% fat and 13 E% protein) within the last 30 min before dosing

It represents an attempt to produce a broader metabolic effect by acting across three pathways rather than one