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6-8 Gastric cytoprotection relies on both endogenous and ingested antioxidants, including vitamin C, so the well-established association between vitamin C deficiency and gastric disease is not suprising

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It may be inappropriate for people with certain endocrine histories, pancreatitis concerns, gallbladder disease, severe gastrointestinal disease, pregnancy, or medication interactions

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Evidence is lacking on the effects of the many dietary supplements on offer, such as vitamins, flavonoids, plant extracts, and trace elements