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It may also contribute to subtle detrimental effects on cognitive function 38 and may have a wide array of other psychiatric manifestations, such as propensity to gamble

[6] Crucially for the systemic story, they then moved into in vivo rodent models

As we age, or when we go through long periods of stress, these natural levels drop

Serotypes such as AAV1, AAV6, AAV8, and especially AAV9 have demonstrated efficient cardiac transduction in small and large animals, enabling robust gene transfer to myocardium with intracoronary or intravenous delivery (Mazurek et al., 2024)

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