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Elevated levels of 5-oxoproline in body fluids

The number of infectious virus particles per mL was calculated as the (MOI cell number)/(infection volume), where MOI = ln(1 infection rate)

Further, the numbers were 35% from anti-estrogenic substances (tamoxifen, clomiphene, fulvestrant, toremifene, and raloxifene) and 20% from AIs (letrozole, anastrozole, exemestane, adrostatrienedione, and armistane) in 2022 (World Anti-Doping Agency, 2024b)

Acknowledgements The figure was generated using BioRender (www.biorender.com/)