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doi: 10.3389/fphar.2022.969107 Received 14 June 2022 Accepted 12 September 2022 Published 03 October 2022 Volume 13 - 2022 Edited by Dan-Qian Chen, Northwest University, China Updates Copyright 2022 Chen, Ye, Wang, Liu, Wang, Wang, Xu and Gong

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After ADCs internalization, hydrazone linkers beak and release cytotoxins due to the acidic environment

Brain 140(11):29272938

These findings underscore the unique pathological timeline and molecular changes in the TgAPParc model, providing a valuable tool for studying Alzheimers disease pathogenesis and therapeutic development