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Lancet 341 , 16071610 (1993)

Sterilizing immunity at high nAb titres One common theme is that high serum titres of nAb (two to three orders of magnitude greater than in vitro nAb titres) are typically required to provide sterilizing immunity in vivo following viral challenge in other words, to completely protect against establishment of infection through complete block of significant viral replication

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2020;16:e043411