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Monogenic IBD typically manifests as very early onset(very early onset inflammatory bowel disease (VEO-IBD)), caused by rare pathogenic variants in genes such as IL10R and X-linked inhibitor of apoptosis protein (XIAP) [193]

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Supplementary Figure S1A), including HbG2 encoding fetal hemoglobin

These needles are usually smaller in gauge and shorter in length compared to IM needles

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