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Curr Neuropharmacol

6 Payers must balance high upfront costs against potential long-term savings from reduced complications

(Previously, Ozempic was being used for weight loss but had only been approved for diabetes.) In the years following approval, a growing number of household names from Oprah to Elon Musk spoke publicly about their positive experiences using GLP-1s for weight loss

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The resultant opening of voltage-dependent L-type Ca 2+ channels increases the intracellular concentration of Ca 2+ , which also acts as a second messenger, augmenting neurotransmitter release [33]

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