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In particular, SSRIs like sertraline (Zoloft) and escitalopram (Lexapro) frequently rank among the top prescriptions for depression and anxiety

Cofactor for L-methylmalonyl-coenzyme A mutase 5-Deoxyadenosylcobalamin is required by the enzyme that catalyzes the conversion of L-methylmalonyl-coenzyme A to succinyl-coenzyme A (succinyl-CoA), which then enters the citric acid cycle ( Figure 2 )

It's also structurally similar to tricyclic antidepressants

He, L., Feng, D., Guo, H., Zhou, Y., Li, Z., Zhang, K., et al

Several commenters indicated they believe the median, 10th percentile, and 90th percentile allowed amounts would be more useful than the estimated allowed amount, better reflecting what hospitals have been reimbursed for items and services

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