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One of the biggest issues with developing diagnostic tools or targeted drugs is off-target effects, said Jefferson Chan, PhD, associate professor of chemistry at the University of Illinois Urbana-Champaign, who conducted the study with graduate student Melissa Lucero

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Desirable in metabolic syndrome models but problematic if glucose stability is a controlled variable

Thus, studies suggest c-MET not only as an anti-tumor target but also a good target for immunotherapy

J Biol Chem (1999) 274(17):114558

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