All trials evaluate weekly subcutaneous retatrutide alongside healthy diet and physical activity counseling
Mounjaro Ph3 trial SURMOUNT showed 95.3% of patients on Mounjaro with prediabetes at baseline reverted to normogylcemia by week 72
Nausea/vomiting, constipation/bloating or diarrhea is one of the most common side effects and unless it is transient, can make the medications intolerable for some
Common side effects reported in clinical trials include gastrointestinal issues such as nausea and diarrhea, which are often temporary as the body adjusts to the medication
Sun Z, Li P, Wang X, Lai S, Qiu H, Chen Z et al (2020) GLP-1/GLP-1R Signaling Regulates Ovarian PCOS-Associated Granulosa Cells Proliferation and Antiapoptosis by Modification of Forkhead Box Protein O1 Phosphorylation Sites
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