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PMID 21719467

NRGN, S100B and GFAP levels are significantly increased in patients with structural lesions resulting from mild traumatic brain injuries

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Llop, Jordi

Research Overview BPC-157 is a partial sequence of a 40 kDa human gastric juice protein originally identified by Sikiri and colleagues in the early 1990s [1]

[Our] basic thinking on AOD9604 is that the drug failed because it was made orally available, which likely reduced bioavailability and also potentially resulted in protein denaturisation in the gastrointestinal tract, which would have reduced the drugs activity