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The 2022 trial also showed that semaglutide helped to lower cholesterol and average blood glucose levels in children with and without diabetes

Therefore, differences in baseline glucose control are unlikely to explain the higher 3P-MACE rate after BI initiation compared to GLP-1RA initiation, and even more so for all-cause mortality

Data availability

Among the 2,000 respondents, 8% (n=155) reported having used a GLP-1 medication to assist with weight loss, with no significant difference in use between men and women

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To investigate this issue Mojsov, Drucker and Habener joined forces with Jacques Philippe and William Chick, two other researchers at MGH