Positron emission tomography of patients with early PD showed a significant increase in the activation of microglia (68), which might lead to neuron loss in PD and AD (69)
The Downsides: Risks, Side Effects, and Concerns Despite the headline-making results, GLP-1 drugs are not without side effects or controversy
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No over-the-counter patch contains semaglutide, liraglutide, or tirzepatide
The drugs mimic a naturally occurring hormone in the body that helps regulate blood sugar and promotes a feeling of fullness
Common Local Reactions The most common local reactions of GLP-1 injections include: Itching Redness Rash Bruising Pain Inflammation or swelling Irritation Small lumps (nodules) Skin thickening Lets take a look at some of these in more detail