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At 70 mg/kg, which is the recommended dose in acute cyanide poisoning, the elimination half-life was 7.36 +/- 0.79 h, the volume of distribution was 0.49 +/- 0.10 L/kg, and the total clearance 0.58 +/- 0.11 L/h

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Soldiers who received high dose early NAC treatment (between 3-4g daily for a week) were 3.6 times more likely to have resolved symptoms of hearing loss, headache, confusion, memory loss, and poor sleep ( 17 )