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These data indicate that GSH depletion is directly responsible for the observed induction of NRF2 activity in Gclc L-KO mice

doi: 10.1016/j.ejpb.2018.10.010 141 NajafiATaheriRAMehdipourMMartnez-PastorFRouhollahiAANouraniMR

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Had she only seen a chiropractor, the underlying metabolic issues would have been missed, and her muscles would have remained inflamed and prone to spasm