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They were originally approved to treat type 2 diabetes by controlling blood sugar, but a host of other benefits were soon discovered, including significant weight loss and reduced risk of cardiovascular disease

A key finding: at 24 weeks, participants had not yet reached a plateau, suggesting the weight loss curve with retatrutide may continue longer than with tirzepatide

TB-500 (Thymosin Beta-4) is a synthetic 43-amino-acid actin-sequestering peptide

GLP-1 RA use was identified as an independent risk factor for food retention (OR 9.19, p = 0.0003)

It slows gastric emptying (keeping you feeling full longer), stimulates insulin release from the pancreas (helping manage blood sugar), and signals the brain to reduce appetite and food intake

Warning signs include a strong fishy smell, bitter or sour taste, and cloudy appearance in liquid forms