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Aesthetic Surgery Journal, 44 (1), 6067
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The Pit-1 ^K216E mouse model exhibits phenotypic features of GHD, including small size, abnormal body composition, and low serum GH
It therefore seems that GLP-1/exendin-4 might be acting in the VMH and LH, interacting with the AMPK/S6K signalling pathways, and modulating the activation status of AMPK and S6K in response to nutrient fluctuations
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