Since then, additional indications have been approved, including adult growth hormone deficiency, Turner syndrome, chronic renal insufficiency, and HIV-associated muscle wasting
Growth Hormone & Igf Research
WARNINGS Patients with early Lebers disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy
A strong evidence of HGF-MET axis importance in the human development of nervous system comes from some studies that reveal a genetic implication of HGF and MET genes in some NDDs such as autism spectrum disorder (ASD), schizophrenia, and non-syndromic hearing loss
This dual role shows the delicate balance between LCs positive and detrimental effects, which is influenced by microbiota composition and metabolic pathways [18, 26, 38]
It is a well-tolerated compound with a clean safety profile and a genuinely interesting mechanism that, so far, has produced results in humans that fall short of what animal models predicted