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The safety profile of GLP-1 injections is well-established, with many individuals experiencing minimal side effects

14,15 Potential Direct Effects on the Heart Although the systemic indirect effects of GLP-1RAs are well established as the primary drivers of their clinical benefit in HF, emerging preclinical and mechanistic evidence suggests GLP-1RAs may also exert some direct cardioprotective effects, as discussed below

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Among these, the type-2 diabetes segment holds the largest share in South Africa diabetes drugs market during the forecast period

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A study in the National Library of Medicine shows that GLP-1 medications lead to a BMI reduction of around 15% to 25%