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The interaction mechanism between AS and depression is highly complex, involving multiple potential mechanisms, including inflammation (Chrysohoou et al., 2018

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however, given that TMAO levels are also greatly influenced by diet-microbiota interactions that are subjected to great variability, the link between TMAO and some human cancers cannot be easily defined (Oellgaard et al., 2017)

Understanding follicular development through multi-omics approaches has revealed complex molecular signatures that reflect ovarian reserve, follicular health, and the aging process, providing clinically relevant biomarkers for fertility assessment and treatment optimization