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A mild effect of the intervention was seen on fatigue while a moderate effect was observed on fatigability

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In positions P +4 and P +6 at the C-terminal side of the P 0 position, two glycine residues (G759 and G761) are positioned such that their amide protons can form interactions with the phosphorylated side chain of T595 within the CDK11 T-loop (Supplementary Fig

suggest that the anti-inflammatory mechanisms induced by TREM2 may be associated with the PI3K-Akt-FoxO3a axis