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Side effects: GLP-1 medications are frequently associated with nausea, constipation, gastroparesis, and, in some patients, significant muscle mass loss alongside fat loss

Drugs like semaglutide , tirzepatide , and retatrutide work by mimicking the GLP-1 hormone, which enhances insulin release, reduces glucagon secretion, slows stomach emptying, and communicates satiety to the brain

We were looking at these rodent studies, and were like, these look really promising. And were doing the math on species conversions to figure out human doses. Nobody was under the illusion that what they were doing was definitively safe, he continued

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If your symptoms center on the gut, our resources on managing gut inflammation may help you understand what is happening