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Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

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Although the exact mechanism by which this stimulates ovulation is not known, it is thought the reduction in ovary size and removal of some follicles results in reduced androgen production, enhanced ovarian blood flow, increased FSH secretion, and restored HPO signaling

Injectable treatments often produce faster results, with some patients noticing improvements within 1-2 weeks

Overexpression of BHMT not only repressed the expression of many mesenchymal markers but also induced the expression of two epithelial markers that were repressed in siHNF4 cells (Fig