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Abstract Purpose of Review Obesity constitutes a global crisis with profound implications on the incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH)

Never stop or start any medication without discussing it with a qualified healthcare provider first

It plays an important role in the body's energy metabolism, specifically in the transfer of fatty acids into cells for subsequent beta-oxidation

This pattern of distribution is likely due to the vascular anatomy of the colon

By understanding your genetic predispositions, you and your provider can time dose escalations to maximize efficacy while minimizing discomfort

In patients discontinuing therapy from maximum dosage of phentermine 15 mg/topiramate 92 mg, gradually taper dosage as recommended to reduce risk of seizures