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Dose-finding studies for CNS effects in humans are needed because extrapolation from rat doses is unreliable

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Info here SKU: BPC5-001 Category: Peptide Specifications About this compound BPC-157 is studied in laboratory settings for its role in cellular repair mechanisms, angiogenesis, nitric oxide signalling, and gastrointestinal biology

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However, observed barrier defects and associated diarrhea even in these mice did not result in changes in claudin-1, -2, -3, and -4 expression and cellular distributions, but rather correlated with the rearrangement of cellular distribution of occludin, and to some extent with JAM proteins